2013年-2017年: 安进中国博士后奖学金。
2012年-2013年: 清华北大生命科学联合中心博士后基金。
代表性论文
1.
Xiangyu Liu*, Ali Masoudi*, Alem W. Kahsai*, Li-Yin Huang, Biswaranjan Pani, Dean P. Staus, Paul J. Shim, Kunio Hirata, Rishabh K. Simhal, Allison M. Schwalb, Paula K. Rambarat, Seungkirl Ahn, Robert J. Lefkowitz#, Brian Kobilka#. Mechanism of β2AR regulation by an intracellular positive allosteric modulator.
Science (2019) 364 (6447), 1283-1287.
2.
Xiangyu Liu*#, Xinyu Xu*, Daniel Hilger*, Philipp Aschauer, Johanna K.S. Tiemann, Yang Du, Hongtao Liu, Kunio Hirata, Xiaoou Sun, Ramon Guixà-González, Jesper M. Mathiesen, Peter W. Hildebrand, Brian K. Kobilka#. Structural insights into the process of GPCR-G protein complex formation,
Cell (2019) 177(5), 1243-1251.
3. Hongtao Liu*, Josefa Hofmann*, Inbar Fish*, Benjamin Schaake, Katrin Eitel, Amelie Bartuschat, Jonas Kaindl, Hannelore Rampp, Ashutosh Banerjee, Harald Hübner, Mary J. Clark, Sandra G. Vincent , John T. Fisher, Markus R. Heinrich, Kunio Hirata,
Xiangyu Liu#, Roger K. Sunahara, Brian K. Shoichet#, Brian K. Kobilka#, Peter Gmeiner#. Structure-guided development of selective muscarinic M3 acetylcholine receptor antagonists.
PNAS (2018) 115(47):12046-12050.
4.
Xiangyu Liu*, Seungkirl Ahn*, Alem W. Kahsai, Kai-Cheng Meng, Naomi R. Latorraca, Biswaranjan Pani, A. J. Venkatakrishnan, Ali Masoudi, William I. Weis, Ron O. Dror, Xin Chen, Robert J. Lefkowitz# & Brian K. Kobilka#. Mechanism of intracellular allosteric β2AR antagonist revealed by X-ray crystal structure,
Nature (2017) 548, 480-484.
5. Yi-He Huang*,
Xiang-Yu Liu*, Xiao-Xia Du, Zheng-Fan Jiang & Xiao-Dong Su#. The Structural Basis for the Sensing and Binding of Cyclic di-GMP by STING,
Nature Structural & Molecular Biology (2012) 19, 728–730.
6. Pontus Gourdon*,
Xiang-Yu Liu*, Tina Skjørringe, J. Preben Morth, Lisbeth Birk Møller#, Bjørn Panyella Pedersen & Poul Nissen#. Crystal structure of a copper-transporting PIB-type ATPase,
Nature (2011) 475, 59-64.
7. Luo Feng*, Gui Xinrui*, Zhou Heng*, Gu Jinge, Li Yichen,
Liu Xiangyu, Zhao Minglei, Li Dan#, Li Xueming#, Liu Cong#. Atomic structures of FUS LC domain segments reveal bases for reversible amyloid fibril formation,
Nature Structural & Molecular Biology (2018) 25 (4), 341–346.
8. Pikyee Ma, Dietmar Weichert, Luba A Aleksandrov, Timothy J Jensen, John R Riordan,
Xiangyu Liu, Brian K Kobilka & Martin Caffrey. The cubicon method for concentrating membrane proteins in the cubic mesophase,
Nature Protocols (2017) 12, 1745–1762.
9. Chia-Ying Huang, Vincent Olieric, Pikyee Ma, Nicole Howe, Lutz Vogeley,
Xiangyu Liu, Rangana Warshamanage, Tobias Weinert, Ezequiel Panepucci, Brian Kobilka, Kay Diederichs, Meitian Wang and Martin Caffrey. In meso in situ serial X-ray crystallography of soluble and membrane proteins at cryogenic temperatures,
Acta Crystallogr D Struct Biol. (2016) 72: 93–112.
10. Bjørn Panyella Pedersen, Pontus Gourdon,
Xiangyu Liu, Jesper Lykkegaard Karlsen and Poul Nissen. Initiating heavy-atom-based phasing by multi-dimensional molecular replacement.
Acta Crystallogr D Struct Biol. (2016) 72: 440–445.
11. Pontus Gourdon, Jacob Lauwring Andersen, Kim L. Hein, Maike Bublitz, Bjørn P.Pedersen,
Xiang-Yu Liu, Laure Yatime, Maria Nyblom, Thorbjørn Terndrup Nielsen, Claus Olesen, Jesper V. Møller, Poul Nissen & J. Preben Morth. HiLiDe - A systematic approach to membrane protein crystallization in high lipid and detergent concentrations.
Crystal Growth & Design (2011) 11 (6), 2098–2106.
